Resources

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Explore these resources to learn more about RASONQUE

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RASONQUE Brochure cover
RASONQUE Brochure
Offers overall guidance about what to expect on treatment.
Download
Care Team Discussion Guide cover
Care Team Discussion Guide
Use this guide to start the conversation about treatment with RASONQUE.
Download
Side Effect Management Guide cover
Side Effect Management Guide
If you're looking to learn more about potential side effects and how to manage them, start here.
Download
Treatment Journal cover
Treatment Journal
Keep track of your treatment schedule, how you're feeling, and any questions you may have.
Download
Rash Management Card cover
Rash Management Card
Supplies details on rash as a potential side effect and how to manage it.
Download
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For caregivers

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Being a caregiver to someone with pancreatic cancer is a challenging yet deeply meaningful role. The role of a caregiver looks different for each person.

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Supporting your loved one may include:
  • Going to medical appointments
  • Reminding them to take their medications
  • Helping them manage side effects
  • Performing household activities, such as cooking or cleaning
  • Providing emotional support
  • Planning leisure activities

No matter what caregiving looks like for you, you are an important part of the care team.

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Caring for yourself, too

To give the best support to your loved one, you need to take care of yourself, too! Here are some tips to keep in mind:

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Downloadable resources for caregivers

Caregiver Booklet cover
Caregiver Booklet
Find tips and resources for YOU, a caregiver, to help support yourself and your loved one during their treatment with RASONQUE
Download
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Look to the cancer community for more support

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Living with pancreatic cancer can feel different than living with other types of cancer

It’s important to be able to connect with people who understand your specific experience. Talking with people in the pancreatic cancer community can help you and your loved ones find support.

These third-party resources are for your information only. Revolution Medicines does not endorse and is not responsible for the content included in these resources. Always talk to your doctor about any questions regarding your treatment plan.

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Frequently Asked Questions (FAQs)

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What is RASONQUE?

RASONQUE is a prescription medicine for adults (18 and older) with a type of pancreatic cancer called pancreatic adenocarcinoma that has spread to other parts of the body and who have received at least one prior treatment or who cannot receive a combination of cancer treatments.

See how RASONQUE was studied in a clinical trial.

Could RASONQUE be right for me?

RASONQUE may be an option for you if:

  • ​You’ve been diagnosed with pancreatic cancer that has spread to other parts of the body (metastatic)
  • You have received chemotherapy for metastatic cancer before

If you’re ready to ask your doctor about RASONQUE, download the Care Team Discussion Guide to help you get prepared and start the conversation.

What does “metastatic” mean?
“Metastatic” means that the cancer has spread to other parts of the body. RASONQUE is approved for pancreatic cancer that is metastatic.
What is RAS?

RAS is found in cells in your body. It sends signals that help cells know when to start and stop growing. Sometimes, these signals can cause cells to grow out of control. This can lead to cancer.

RASONQUE targets RAS that is mutated and RAS that is normal (without a mutation).

Learn more about the role of RAS in pancreatic cancer and how RASONQUE targets RAS.

How was RASONQUE studied in the clinical trial?

RASONQUE was studied in a clinical trial that included 500 adults:

  • ​With pancreatic cancer that has spread to other parts of the body (metastatic)
  • Whose cancer progressed after prior chemotherapy
  • Whose cancer did or did not have a RAS mutation*

People in the study received either RASONQUE (orally, once daily) or chemotherapy (by infusion).

*The trial included 459 people whose cancer had a RAS G12 mutation and 41 people whose cancer did not have a RAS G12 mutation.

The chemotherapy that people received was chosen by their doctor from the following combinations: modified FOLFIRINOX (leucovorin + fluorouracil + irinotecan + oxaliplatin); gemcitabine + nab-paclitaxel; FOLFOX (leucovorin + fluorouracil + oxaliplatin); or liposomal irinotecan + fluorouracil/leucovorin.

Learn more about the clinical trial results.

What are the most common side effects of treatment with RASONQUE?

The most common side effects of RASONQUE include: rash, diarrhea, swelling or sores in the mouth, nausea, tiredness or weakness, vomiting, stomach (abdominal) pain, swelling in the arms and legs, decreased appetite, and bleeding. The majority of people who received RASONQUE had skin reactions, including rash.

RASONQUE can cause serious side effects, including: skin reactions, swelling or sores in the mouth (stomatitis), diarrhea, tears in your stomach or intestines (gastrointestinal perforation), and lung or breathing problems (pneumonitis). RASONQUE can harm your unborn baby.

These are not all the possible side effects of RASONQUE.

Learn more about side effects.

How do I take RASONQUE?

RASONQUE is taken orally, once daily, with or without food. Take RASONQUE exactly as your doctor tells you to take it. Do not change your dose or stop taking RASONQUE unless your doctor tells you to.

Learn more about taking RASONQUE.

How does RASONQUE work?

RASONQUE is a targeted treatment. Targeted treatments work differently than chemotherapy.

Chemotherapy kills or slows the growth of cells that are growing quickly, including cancer cells and healthy cells.

Targeted treatments like RASONQUE seek out and attack specific cells that cause cancer to grow. Because they look for these cells, they are less likely to affect healthy cells.

Learn more about RAS.

Who makes up my care team?

Your care team may include an oncologist, physician assistants, nurses and nurse practitioners, nurse navigators, pharmacists, and a dietitian/nutritionist. Everyone on your care team has the same goal: to help you manage side effects and continue with treatment.

You and your caregiver are the leaders of your team! Make sure to use your voice and connect with your care team when you need to.

Learn more about side effects and connecting with your care team to help them.

Are there any financial support services for RASONQUE?

For financial support services for RASONQUE, enroll in the (ON)Path Patient Support Program with the help of your provider. (ON)Path can help connect you with reimbursement services, commercial copay resources, and other patient assistance resources.

Learn more about support services available during your treatment with RASONQUE.

Can RASONQUE be delivered by a specialty pharmacy?

Yes, RASONQUE can be delivered by a specialty pharmacy.

Learn more about how you can work with your specialty pharmacy to ensure delivery of RASONQUE.

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